Literally, almost a hundred or so explore papers or curative reviews come across my desk every combine of days. I guess you can say I gather them. See, whenever I meet man in the curative field, I always make sure I leave my e-mail address with them just in case they come across any facts with regard to nutraceuticals. I like to read everything. As they say, knowledge is power.
Thus, rarely do I get excited about an herbal product. It takes a lot to earn my trust, let alone my hard-earned money. There has to be a titanic amount of evidence supporting the herbal before I'd even think twice about testing it. There's too much rift-raft in the dietary supplement industry. I was fooled long ago while my "believe every miracle cure a marketer throws at me" days. I'm much wiser now. I can cut through the Bs and get right down to the good stuff.
News From Armenia
I must admit though, I'm unquestionably excited about this first ingredient in my "stress less for poker success" formula. The explore in not only animals but also humans is very convincing. The science, the feedback, all is very sound. All I can say is "I'm a believer."
Rhodiola Rosea
I just want to give you a quick overview about this ingredient. These are things you need to know so you can best evaluate either it can benefit your game. I'll then tell you why I love this ingredient for poker players.
Introduction
Rhodiola Rosea, a plant, is typically found in the mountain regions throughout Europe and Asia. It's been used for years in former Asian and Eastern European medicine. In addition, it's been studied for over 35 years in Russia and Scandanavia, with a large majority of the explore not yet translated. Now remember, the Russians were studying and using anabolic steroids well before the U.S. Even knew what testosterone was. When it comes to carrying out enhancing supplements, Russians are ordinarily near the forefront of innovation.
Mechanism of action
I want you to try something. Stop reading this, put on your running shoes, and go outside. Yes, do it. It'll make this record mean so much more. Now run as far as you can until you feel like you're going to die. Stop, and I want you to do some involved arithmetic. How about the first ten U.S. Presidents? Ok, something a microscopic easier. How about your first, middle, and last name? Tough, isn't it? That's what stress can do to your mind. Now continue reading.
Rhodiola Rosea is classified as an adaptogen, due to its quality to increase resistance to a host of chemical, biological, and physiological stressors. In layman's terms, it protects you from all kinds of stress in a variety of ways. Adaptogens help keep the body in a state of salutary balance. When there's too much stress, it helps counteract it. When there's too microscopic stress, it helps the body increase its stress response.
Just a few of the suggested ways it works include:
Its quality to stop the enzymes responsible for the destruction of norepinephrine, epinephrine, and dopamine, along with helping in the vehicle of those neurotransmitters. All three neurotransmitters are vital to thinking performance. Think caffeine or stimulants when you hear the words norepinephrine and epinephrine.
Its quality to help minimize the loss of norepinephrine and epinephrine from the adrenal gland while times of acute stress. This is particularly important since one of the most influential doctors in the U.S. Stated that there's an adrenal fatigue epidemic in the U.S. Any help your adrenal gland can get is highly beneficial to your health.
Its quality to induce opiod peptide biosynthesis, along with activating peripheral and central opiod receptors. Yes, you heard me right. I said opiod.
Here's a quick analogy that helps when trying to figure out exactly what Rhodiola Rosea does. Have you every worked out after a long break and got sore as all hell? Then, after a few weeks of working out, even though you are doing the exact same habit as you did when you got sore the first time, you don't even feel like you're breaking a sweat. That's adaptation. Rhodiola Rosea does almost the exact same thing, but its effects are more thinking as opposed to physical. It gives your body that extra help it needs to fight intense stress. It readies the defenses even before you taste the stress.
Dosage
Because it helps keep the body in a salutary balance, you'll get the most benefit from a mid-range dosage, even though some newer studies are showing effectiveness in treating depression and normal anxiety disorder with higher dosages. Typically, you'll want to stay in the dosing range of 100-170mg extract standardized to 3.6% rosavin. Some of the literature suggests doses lower and higher than that range are equally ineffective. The most important aspect to pay concentration to is the division of rosavin.
Because Rhodiola rosea is a plant, there are numerous compounds that have shown pharmacological effects within the plant. Thus, to help standardize the dosage, the division of rosavin was chosen because it's almost unique to this single species of Rhodiola. Think of it as the proof of alcohol. I'm sure you and I both know what that means.
Also, if you are using Rhodiola Rosea for acute stressful situations, typically you'll want to use 3 times the daily dosage. Unlike most other adaptogens, Rhodiola Rosea has been shown to be productive in acute stressful situations, not just while persisting stress.
It's also best to cycle your usage of Rhodiola Rosea. It's been used up to four months at a time. I suggest using it while times of intense stress, such as while poker tournaments that may end up being all-nighters, etc. I personally don't use it all the time. I like to rely on it when I'm working on major presentations or when I know I'll have a combine weeks of hell. It's been a lifesaver. So far, the only side effects noticed were irritability and insomnia. I interrogate either the dosage was too high or the patients even unquestionably needed it.
Why I like it.
It doesn't just work centrally like most other adaptogens. It also works peripherally. Thus, it's great to stack with other adaptogens. Synergy at its finest.
It just doesn't work while periods of prolonged stress. It also works for acute stressful situations. Very convenient.
The animal studies have provided perfect evidence. The human studies have been even better. It's been studied on physicians, students, and salutary 19-21 year-olds. If that wasn't enough, the large majority of the explore from Russia and Scandanavia hasn't even been translated yet. Thus, we're just starting to see the tip of the iceberg.
Within the last combine of years, it's even been studied to treat normal anxiety disorder and depression. Very few herbal supplements unquestionably make it to "disease studies." This is equivalent to the stage 2 and 3 clinical trials prescribe medications are tested in. The astounding part was both studies showed beneficial effects for both curative conditions.
It helps to balance the body. It doesn't take the body out of its natural state. Side effects are minimal.
Why do I Love it for poker players?
I don't care how much you love poker, it's stressful. No one enjoys losing money. Tell me if some of these benefits wouldn't heighten your game: stimulation of the nervous system, alleviating depression, minimizing thinking and physical fatigue, enhancing work performance, and enhancing sleep difficulties. Just one of those effects will probably have quite an impact on your poker game. Animal studies have even suggested some cognitive enhancing effects. Now that's what I consider a carrying out enhancing supplement for the poker world.
If you play poker regularly, you probably have a sporadic lifestyle. You can't plan when you're going to play in tournaments or pick-up games. They sometimes appear out of nowhere. Rhodiola rosea works while times of acute stress and periods of prolonged stress. Did you say you need instant stress relief while this intense tournament? Try Rhodiola Rosea. Wait, did you say you needed some stress relief while this month long run of bad cards? Try Rhodiola Rosea. It's very, very convenient.
The feel-good effects of dopamine, the vigor of norepinephrine and epinephrine, the antidepressive feelings of serotonin, and the euphoria of opiods. All balanced by Rhodiola Rosea. Now that's good stuff.
I think I've rambled on enough about my top ingredient for the stress less for success formula. Stress can do some nasty things to the mind. If it's hurting your poker game, you need this formula. If you're losing sleep from poker, you need this formula. It's worked for me and I'm sure it will work for you.
Clinical Studies
Here a combine Rhodiola rosea studies that I referred to in the former article. I just want to get them up tonight so you can read them. I'll go into a microscopic more information about them tomorrow.
1) A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic consequent of Rhodiola rosea Shr-5 extract on the fatigue of students caused by stress while an examination period with a repeated low-dose regimen.
Spasov Aa, Wikman Gk, Mandrikov Vb, Mironova Ia, Neumoin Vv.
Volgograd curative Academy, Russia.
The objective was to explore the stimulating and normalizing consequent of the adaptogen Rhodiola rosea extract Shr-5 in foreign students while a stressful examination period. The study was performed as a double-blind, randomized and placebo-controlled with low repeated dose regime. The study drug and the placebo were taken for 20 days by the students while an examination period. The physical and thinking carrying out were assessed before and after the period, based on objective as well as on subjective evaluation. The most needful correction in the Shr-5 group was seen in physical fitness, thinking fatigue and neuro-motoric tests (p Rhodiola rosea in stress induced fatigue--a duplicate blind cross-over study of a standardized extract Shr-5 with a repeated low-dose regimen on the thinking carrying out of salutary physicians while night duty.
Darbinyan V, Kteyan A, Panossian A, Gabrielian E, Wikman G, Wagner H.
Department of Neurology, Armenian State curative University, Yerevan. Epilepsy@acc.com
The aim of this study was to explore the consequent of repeated low-dose treatment with a standardized extract Shr/5 of rhizome Rhodiola rosea L, (Rre) on fatigue while night duty among a group of 56 young, salutary physicians. The consequent was measured as total thinking carrying out calculated as Fatigue Index. The tests chosen reflect an widespread level of thinking fatigue, fascinating involved perceptive and cognitive cerebral functions, such as associative thinking, short-term memory, calculation and quality of concentration, and speed of audio-visual perception. These parameters were tested before and after night duty while three periods of two weeks each: a) a test period of one Rre/placebo tablet daily, b) a washout period and c) a third period of one placebo/Rre tablet daily, in a double-blind cross-over trial. The perceptive and cognitive cerebral functions mentioned above were investigated using 5 dissimilar tests. A statistically needful correction in these tests was observed in the treatment group (Rre) while the first two weeks period. No side-effects were reported for either treatment noted. These results suggest that Rre can cut normal fatigue under determined stressful conditions.
3) A pilot study of Rhodiola rosea (Rhodax) for generalized anxiety disorder (Gad).
Bystritsky A, Kerwin L, Feusner Jd.
Department of Psychiatry, University of California, Los Angeles, Ca, Usa. Abystritsky@mednet.ucla.edu
Background: Rhodiola rosea is an herbal supplement that many in the normal citizen in Russia and elsewhere in the world have used for decades to alleviate everyday anxiety, depression, and insomnia. either R. Rosea is productive in reducing similar symptoms in clinical samples is unknown. The goal of this pilot study was to evaluate either R. Rosea is productive in reducing symptoms of generalized anxiety disorder (Gad). Method: Ten (10) participants with a Dsm-Iv pathology of Gad, recruited from the Ucla Anxiety Disorders agenda and in the middle of the ages of 34 and 55, were enrolled in this study from November 2005 to May 2006. Participants received a total daily dose of 340 mg of R. Rosea extract for 10 weeks. Assessments included the Hamilton Anxiety Rating Scale (Hars), the Four-Dimensional Anxiety and Depression Scale, and the Clinical Global Impressions of Severity/Improvement Scale. Results: Individuals treated with R. Rosea showed needful decreases in mean Hars scores at endpoint (t=3.27, p=0.01). Adverse events were generally mild or moderate in severity, the most tasteless being dizziness and dry mouth. Conclusions: needful correction in Gad symptoms was found with R. Rosea, with a allowance in Hars scores similar to that found in clinical trials. These preliminary findings guarantee added exploration of treatment with R. Rosea in clinical samples.
4) Clinical trial of Rhodiola rosea L. extract Shr-5 in the treatment of mild to moderate depression.
Darbinyan V, Aslanyan G, Amroyan E, Gabrielyan E, Malmström C, Panossian A.
Department of Neurology, Armenian State curative University, Yerevan, Armenia.
The objective of this study was to assess the efficacy and protection of standardized extract Shr-5 of rhizomes of Rhodiola rosea L. In patients suffering from a current part of mild/moderate depression. The phase Iii clinical trial was carried out as a randomized double-blind placebo-controlled study with parallel groups over 6 weeks. Participants, males and females aged 18-70 years, were superior agreeing to Dsm-Iv diagnostic criteria for depression, the severity of which was determined by scores gained in Beck Depression catalogue and Hamilton Rating Scale for Depression (Hamd) questionnaires. Patients with preliminary Hamd scores in the middle of 21 and 31 were randomized into three groups, one of which (group A: 31 patients) received two tablets daily of Shr-5 (340 mg/day), a second (group B: 29 patients) received two tablets twice per day of Shr-5 (680 mg/day), and a third (group C: 29 patients) received two placebo tablets daily. The efficacy of Shr-5 extract with respect to depressive complaints was assessed on days 0 and 42 of the study period from total and specific subgroup Hamd scores. For individuals in groups A and B, widespread depression, together with insomnia, emotional instability and somatization, but not self-esteem, improved significantly following medication, whilst the placebo group did not show such improvements. No serious side-effects were reported in any of the groups A-C. It is fulfilled, that the standardized extract Shr-5 shows anti-depressive potency in patients with mild to moderate depression when administered in dosages of either 340 or 680 mg/day over a 6-week period.
5) Efficacy and tolerability of a Rhodiola rosea extract in adults with physical and cognitive deficiencies.
Fintelmann V, Gruenwald J.
Carl Gustav Carus Akademie Hamburg e. V., Hamburg, Germany.
During a 12-wk drug monitoring study, the efficacy and protection of a Rhodiola rosea extract given in mixture with vitamins and minerals (vigodana(R)) were tested in 120 adults (83 women and 37 men, ages 50-89 y) with physical and cognitive deficiencies. Two dissimilar dosage regimens were chosen. One group of 60 patients (group 1) took 2 capsules orally in the morning after breakfast, and the other group (group 2) took 1 capsule after morning meal and 1 after lunch. Three curative examinations were performed while the procedure of the study (at baseline, after 6 wk, and after 12 wk). The evaluated symptoms were divided into physical disturbances such as exhaustion, decreased motivation, daytime sleepiness, decreased libido, sleep disturbances, and cognitive complaints (eg, concentration deficiencies, forgetfulness, decreased memory, susceptibility to stress, irritability). A statistically highly needful correction (Pa randomized trial of two dissimilar doses of a Shr-5 Rhodiola rosea extract versus placebo and control of capacity for thinking work.
Shevtsov Va, Zholus Bi, Shervarly Vi, Vol'skij Vb, Korovin Yp, Khristich Mp, Roslyakova Na, Wikman G.
Centre of sanitary and Epidemiological Inspection of the R.F. Ministry of Health, Moscow, Russia.
A randomized, double-blind, placebo-controlled, parallel-group clinical study with an extra non-treatment group was performed to measure the consequent of a single dose of standardized Shr-5 Rhodiola rosea extract on capacity for thinking work against a background of fatigue and stress. An added objective was to explore a possible unlikeness in the middle of two doses, one dose being chosen as the appropriate mean dose in accordance with well-established medicinal use as a psychostimulant/adaptogen, the other dose being 50% higher. Some physiological parameters, e.g. Pulse rate, systolic and diastolic blood pressure, were also measured. The study was carried out on a highly uniform citizen comprising 161 cadets aged from 19 to 21 years. All groups were found to have very similar preliminary data, with no needful unlikeness with regard to any parameter. The study showed a pronounced antifatigue consequent reflected in an antifatigue index defined as a ratio called Afi. The verum groups had Afi mean values of 1.0385 and 1.0195, 2 and 3 capsules respectively, whilst the figure for the placebo group was 0.9046. This was statistically highly needful (p My Opinion
As always, I'd just like to add my two cents about some of the trials I posted on my former entry. I'll keep it short.
Study 1: the students
One of the few slights I have against this study is the amount of participants, 40. In the prescribe drug world, I'm used to finding at least any hundred participants, ordinarily any thousand. However, that's an highly expensive and long process. It'd be hard for any natural product to get that kind of funding. Like I said before, without patents, there's no money in proving natural products work.
The good news is though that the study looked at any dissimilar aspects of thinking well-being through objective and subjective tests. Rhodiola rosea improved physical fitness, psychomotor function, thinking performance, and normal well-being as well as reducing thinking fatigue, sleep requirements, and abnormal sleeping habits. Subjects also said they were in a great mood as well as being more motivated to study. Also, the students who used Rhodiola rosea had an 18% higher median score than the control group. However, because of the small size, that last note should be taken with caution.
The most important aspect of this trial is the subjects themselves. All of the students were curative students. Thus, they know what the placebo-effect is (basically meaning the benefit isn't necessarily from the treatment itself, but it's from your mind). Being trained to detect and minimize it, the results were still unquestionably needful for Rhodiola rosea. In addition, former U.S. treatment typically frowns upon natural products. Thus, if anything, the students would be biased against Rhodiola rosea.
It was a small study, but I was very impressed with the results. Taking into the catalogue of all the determined benefits it showed and who the subjects were, I'd overlook the small sample size.
Study 2 - salutary physicians
I take great joy in proving that natural supplements do have their place in former medicine. Thus, inspecting this study was done on physicians, and it showed statistically needful improvements, I almost cried when I read this study.
Once again, the microscopic against this study is the small sample size, 56. However, because it was studied on physicians, I have to overlook that. Trust me, most physicians are almost vehemently against using natural products. I've spent many hours on the phone convincing physicians that patients will get the same benefit from fascinating fish oil capsules as they would the prescribe drug Lovaza (which is basically pharmaceutical grade fish oil) without the added expense. You would not believe how brainwashed some of these physicians are by drug companies.
Once again, this study looked at any dissimilar parameters together with speed of optical and auditory perception, concentration capacity, and short-term memory, and then used the results to infer a Fatigue Index. Again, Rhodiola rosea showed statistically needful improvement. After the preliminary two week test, the authors then did a 2 week wash-out period and retested the physicians. As expected, the tests returned to baseline added supporting the effects of Rhodiola rosea.
However, the one knock is after the two week washout period, the authors had someone else two week test with Rhodiola rosea. This time it didn't offset the decline in thinking performance. I have yet to decree a infer as to why. I'm still working on it.
Once again, I feel the small sample size is overshadowed by the subjects and the results. In my opinion, these two studies were great for poker players. Physicians, especially interns, are put under a great deal of thinking and physical stress much like poker players. They have poor sleep habits, their minds are constantly working, their juggling manifold situations, and the stress from the head physicians is unbelievable. If there's one class of citizen that are like poker players, physicians would be as close as you can get.
Study 3 and 4 - Gad and depression
These studies pretty much speak for themselves. In both studies, patients were clinically diagnosed with depression or normal anxiety disorder. The dosages were higher than in the other studies. They showed correction in both conditions. The downside: they also both had small sample sizes. I predict that these studies are going to lead to larger studies done in both of these populations.
The most important thing to take away from these studies: the small amount of side effects associated with those high doses (dry mouth and dizziness). Very impressive. Very safe.
Study 5 -
There were unquestionably any good things that came out of this study. First, it suggested that taking one dose is great than splitting your doses in half and taking them twice daily. Secondly, not only did the patients say Rhodiola rosea worked (80% of them), but so did 81% of the physicians. Once again, it brought a tear to my eye. Finally, the study showed a needful correction in not only physical deficiencies, but also cognitive deficiencies, which added supports Rhodiol rosea's non-specific anti-stress actions.
Downsides: Small sample size, 120. It also wasn't a double-blind placebo controlled trial, the gold-standard in medicine. It basically monitored the patients. However, the 80% success rate is hard to ignore.
Study 6 - cadet study
Once again, it suffers from a small sample size, 161. However, they were young and salutary 19-21 year-old cadets. It always makes a study that much stronger when it shows a benefit in young, salutary adults. It makes it easier to extrapolate the data to the majority of the population.
Once again, the authors calculated an anti-fatigue index. treatment of Rhodiola rosea resulted in over a 10% reduction, which was statistically highly significant. Also, it showed a trend toward more benefits with the lower dosage, added supporting the balance behind Rhodiola rosea.
I unquestionably do love all of these studies. Even taking into catalogue the small sample sizes, I still have to think they highly favor Rhodiola rosea. I feel these results can unquestionably be extrapolated into the poker community. For pete's sake, these studies were done on physicians, curative students, and young cadets. What great models than these for poker players?
Like I said before, I get unquestionably excited by very few natural supplements, may be one of out every 100-200 that I come across. Rhodiola rosea is at the top of my list. I suggest it to all of my athletes, poker players, physicians, pharmacists, and other professionals I consult for. I unquestionably believe in this supplement. The science supports it. The clinical studies hold it. Most importantly, the real-world feedback supports it. Try it out. See for yourself. Remember, give it a combine weeks, and find the right dose for you.
If you do happen to use it, I'd love to hear some feedback, negative or positive. I'm particularly finding for what dosage worked best for you. Good-luck and may you get the cards you need.
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